I also have both a Kindle (original one) and the ipad2 with the kindle app. I have carpal tunnel and the kindle is much easier on my hands. It is more difficult to find a comfortable position to read the ipad2. I even went out and bought a stand to use for reading, but then I have to sit on a harder chair at my kitchen table. So reading is on the kindle, unless I have the ipad out somewhere. And I love the ability to go where I left off reading, regardless of what device is with me.