Hi all- As a veteran of web forums I made sure to read through lots of threads about this, including the apple support suggestions and I'm still stuck. I have an iMac desktop and an iPad 1st gen. I am running the most recent version of iTunes (10.2.1), the most updated version of OSX (10.6.7), and the most recent version of IOS (4.3) on my iPad (1st gen). I have gone through all of the uninstalls and re-installs that apple suggests on their support site, as well as all of the resetting and restarting of the iPad and iMac. I've tried different USB ports, different USB cords, etc. iTunes is still not recognizing the iPad, and the iPad does NOT show any indication that it is connected (no charging icon, etc). iTunes DOES recognize my iPod nano (4th gen), and the iPad DOES charge in a wall charger with the standard Apple usb cable and wall charger setup. I don't connect the iPad to iTunes too often (maybe once a week on average), but this all worked last time it was connected. Did I run any software updates since then? I'm not certain. Any help would be greatly appreciated - I'm baffled.