The iPad2 was crashing out of the mail program every time I tried to open it. it would open for a minute then close on its own. So general rule of thumb, when electronics get twitchy ... reboot so I used Sbsettings to reboot. now I am stuck watching the spinning circle for FAR too long !
EDIT ... when I plug it into the PC I get a cannot connect error 0xE8000065 !
Further Edit ... All is now well a reset of pad (hold home and power till screen goes black) seems to have allowed me to regain control.