I use the Zagg leatherskin for the back of my iPad - and it's the only thing I use. I don't feel uncomfortable using it that way. Actually, the leatherskin makes the iPad a little bit "grippier" so I don't feel as if it is going to slip out of my hands. I just like the look and feel of a naked iPad.
OK. You know, re-reading that ... I'm not too sure I should be saying stuff like that on a public forum!
Oh, and when I go out of the house, I do "cover" up the iPad with a Zaggmate keyboard/case. So, it's not like it's running around all naked and stuff in public...