I have a similar issue with the mkv video format and certain apps, if the file is in GoodReader or similar and I use the open in feature, the registered media apps will not show up. This is on my iPad 2. The weird thing is with the exact same set up on my iPad 1, the media apps do show up as possible destinations. I worked with one of the media app devs and we were unable to get to the bottom of this. It seems like the app registration for the open in feature is a little flaky.

First tap on the PDF in Mail and let it download. Then tap and hold on it. Does this give you the Open in... pop-up?

@info: I tried but the file downloads as a bunch of symbols and when i press and hold it only selects everything but doesnt give me the option of open in

Originally Posted by chelism

@info: I tried but the file downloads as a bunch of symbols and when i press and hold it only selects everything but doesnt give me the option of open in

Well, donka refers to what seems to be a known problem above. Have you closed all programs and rebooted and tried again with the same result? Can you email yourself a different PDF and reproduce the same result?