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I click on the icon on the home screen and the screen pops up with the chasing circle and it says "Loading..." but it never does anything.
I can open the App Store and I have iTunes loaded on my computer. I can sync it, but the app won't open.
This is my first Apple product. Am I missing something simple?
Welcome from Australia. Please try holding power button and home key down until you see a white Apple logo then release the keys. After restart try opening iTunes. If this fails connect to your computer and do a restore after back up. Hope that helps.
It is also possible you do not have an Internet connection. The iTunes app needs to connect to the apple servers to get the current data to display.